Nigella Sativa on the Improvement of Ovarian Dysfunctions in Polycystic Ovary Syndrome (PCOS): A Short Review

Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder that is commonly diagnosed in women of reproductive age. The reported incidents of PCOS are drastically increasing every year worldwide, however, the etiology of PCOS is still not fully comprehended. A traditional herb such as Nigella sativa (NS) is being consumed as an alternative to modern medications to manage the signs of PCOS. The effectiveness of NS against PCOS signs and symptoms is being widely published, but studies focusing on its effect on ovarian dysregulations are limited. Hence, this review was written to provide an updated summary of NS and the ovaries of PCOS subjects. This review gathered publications from studies conducted in an in vivo and clinical trial settings and is anticipated to be a reference for future research involving NS and PCOS subjects.