In this study, we examined the gender role and the effects of climate change adaptation practices on small-scale vegetable farmers in Delta State. Specific objectives were to; estimate the determinants of climate change adaptation strategy; (ii) examine the resilience level of vegetable farmers by gender and analyze the impact of climate change on net farm income of vegetable farmers. A purposive sampling procedure was adopted where Ethiope East, Okpe, and Uvwie local government areas were selected from Delta Central Agricultural Zone. 119 vegetable farmers were selected for the study. In the regression analysis, descriptive statistics and Multinomial and Binary Logistic Regression Model were used to analyze the data collected during this study. Using the likelihood ratio Chi-square value of 68.5722 as a result of the determinant of climate change adaptation practices, the multinomial regression model fits accurately in estimating the determinant of climate change at a 1 percent probability level. As a result of binary logistics regression, the Black Chi was significant at 1 percent. This means that climate change events have affected vegetable farmers’ income negatively. This therefore calls for more effort from the government to strengthen the provision of agricultural extension services by improving its climate information system, providing recommended agricultural inputs and training farmers on best agronomic practices to enhance their holistic adaptation to the effect of climate change.