A rare familial multisystem neurodevelopmental disease known as Williams-Beuren's syndrome affects people of all racial and ethnic backgrounds and both sexes equally. A thirteen-year-old man presented to Prince Sultan Military Medical City to the psychiatric department with common mental health comorbidities and suffered from psychosis. It is a known case of WB Syndrome. It was recommended for a follow-up referral to pediatric cardiology consultation to follow up on the case and also to assess the safety of starting him on stimulants vs. Strattera for ADHD. Neurology impression is needed to figure out if there is any other medical cause of hallucination and to neurology to discover any other organic causes of such hallucinations. The condition was explained to both mothers and determined if there is any other medical cause of hallucination and the child; they are in agreement with the plan. The present study is the first Williams-Beuren syndrome in our hospital. Our results indicate that specific psychotic episodes are part of Williams-Beuren's syndrome.
