This article proposes a method with the integration of PSO and fuzzy optimization to provide decision support in project risk response. The main steps of the method included: (1) formulation of alternative risk response actions based on PSO, and (2) determination of the optimal set of RRAs using a fuzzy optimization model. In this method, project managers can find alternative RRAs and further determine the optimal set of RRAs. Some managerial suggestion and implication are drawn from the results of the article. First, to perform better risk response in the future, it is suggested that organizations should always capture a long-term perspective, with an awareness of keeping documents of all handled historical projects. Second, because any RRA obtained from alternative historical cases must be adapted to the existing situations, adaptation costs must also be considered when allocating budget for selecting RRAs.